Tag Archive: tuberculosis

Jun
05

The war against Tuberculosis needs new drugs

This is not a call to arms for a war fought with bombs and bullets, but one which is equally catastrophic in terms of human loss. We are fighting armies of microscopic bacteria called Tuberculosis (TB) that knows no country boundaries, infecting 9 million and killing 1.5 million per year. Human kind has only defended …

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May
01

The next generation of Tuberculosis researchers

I like to help and mentor students in various ways when I can. Over the years this has lead to some fun projects and computational models. For a long time I have been an Adjunct Associate Professor at the University of Maryland, yet today I heard about a group of undergraduates there working on Tuberculosis. …

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Dec
15

A year in publications – 2014

A year in collaborative publications, the ups and downs and a few random comments as well (with a big thanks to all involved): 1. Ekins S and Freundlich JS and Coffee M, A common feature pharmacophore for FDA-approved drugs inhibiting the Ebola virus, F1000research, 3: 277, 2014. This came initially from a Twitter exchange of …

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Apr
07

CDD community meeting presentation

Last Friday was the CDD community meeting held in San Francisco. It was a full day of presentations on many different topics ranging from collaboration, neglected disease drug discovery and beyond. It was the third community meeting I have attended and I really thought it was great for discussions and interaction between the speakers, panels …

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Mar
24

World TB day

Today is World TB day. Links can be found for the Stop TB Partnership World TB Day.org CDC WHO USAID I do not have a lot to say except – please let others know.   Update: I tweeted the following today: World TB day 1. raise awareness that we need a bigger pipeline TB Alliance …

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Mar
12

ACS in Dallas

Well, its not quite the last minute but I have been working on putting slides together for the one talk I will be giving on Sunday at the ACS. Its called “Looking back at Mycobacterium tuberculosis mouse efficacy testing to move new drugs forward” and will be presented at 3.15pm in the Omni Dallas Hotel …

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Mar
07

Approval of Bedaquiline in the EU: Time for a regulatory rethink?

I note that yesterday J&J got a conditional approval on their tuberculoisis (TB) drug Bedaquiline. You may remember that this drug was approved by the FDA in late 2012 and represents a new treatment for multidrug resistant TB. One wonders why the EU took over a year longer, was their more concern with some of …

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Feb
20

TB Mobile version 2.0

One minute it’s submitted to the AppStore, then its approved and available already. It is amazing how fast these things can happen! Yes you are wondering what is it, well its TB Mobile version 2.0 *. When the Idea appeared to develop the TB Mobile app in 2012 I had no idea that we would …

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Jan
29

AstraZeneca to shut down R&D site in Bangalore

I was just informed that some of our collaborators in the MM4TB project will be losing their jobs as AZ closes the site in India. While I totally understand that no job is for life, there is no stability in pharma anymore and it does not matter if you are in the UK, USA or …

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Jan
17

SLAS 2014

On Sunday I will be heading to the Society for Laboratory Automation and Screening (SLAS) 2014 meeting in San Diego. It will be a very quick trip to give a talk on Monday “Cheminformatics Workflows Using Mobile Apps for Drug Discovery” followed by a poster in the afternoon “Dual Response and Dataset Fusion for Machine …

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