Tag Archive: tuberculosis

Mar
16

Drug Discovery Today Special Issue on Tuberculosis

Today a special issue of Drug Today Today was published. I was  the editor of this issue and honored that so many colleagues from our European funded MM4TB and other European projects agreed to provide articles on their contributions to Tuberculosis drug discovery. Through collaborations I was directly involved in providing 3 articles and an …

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Nov
07

Non-classical transpeptidases insights and new antibacterials

Well today’s post has been a few years in gestation and yes I have had to keep it quiet for a long, long time which was extended as our recent paper was embargoed for what seemed like an eternity. It starts back in 2009 when I was using some of the NIAID/SRI whole cell screening …

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Aug
16

Collaborations Pharma, Inc. And Rutgers Announce NIH Award to Develop Treatments for Tuberculosis

To follow up my last post .. I can now announce some recent funding from NIAID for the TB work with Dr. Joel Freundlich ! Here is the PR – Fuquay-Varina, North Carolina – The National Institute of Allergy and Infectious Diseases (NIAID) recently awarded $149,388 to Collaborations Pharma, Inc. (CPI) to initiate a partnership …

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Jun
27

MM4TB and a trip to a new Miro Exhibit

  Occasionally I take a bit of a diversion from my usual science focused postings, this one has an artistic flavor. I am in beautiful Brataslava in the Slovak Republic for a few days for the final More Medicines for Tuberculosis (MM4TB) meeting. Every 6 months for the past 5 years we have had meetings of …

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Dec
28

2015 in review

2015 saw the continuation of some research themes from 2014, namely some work on Ebola, rare diseases and Bayesian models for neglected diseases. At the end of the year several papers are in press for next year so more to come. As usual there were some ups and downs in getting some of these to see …

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Jul
30

My experience of submitting another manuscript to PLOSONE

Its been several years since I last submitted to PLOSONE . Since then we embarked on a Phase II grant working on tuberculosis and after much work by many labs at Rutgers and SRI we are now submitting the work today. So we decided to give PLOSONE a second chance. In the interim I have …

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Jul
16

What’s needed for TB: A critical analysis of the drug discovery pipeline and efforts

After attending the Gordon conference on Tuberculosis (TB) drug discovery (without breaking the rules on describing what was presented) I think I can safely make a few general comments which were already in my mind before the meeting. This week what stood out for me was the lack of knowledge of all the efforts that …

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Jul
13

Waging war on infectious diseases

While I am at the Gordon Conference on Tuberculosis (TB) Drug Discovery and Development this week I cannot live Tweet due to their policy. I do however have some thoughts based on my observations. This is not a war fought by soldiers armed with guns and artillery against an enemy similarly armed, this is a …

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Jul
09

Observations on big and small collaborations

Its been a pretty hectic year to date with several grants coming to their conclusion and the need for writing up final reports and manuscripts. In addition it has provided just a little time for reflection. Pretty much everything I am involved in is a collaboration of some sort so I am just a tiny …

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Jun
10

The Case for Why the EC Needs to Fund Small Molecule TB Drug Discovery

My previous post may have been too refined..so let me revert to a drier scientific style. In the last few weeks Iain Old, Giovanna Riccardi, myself and several others from the MM4TB project have been lobbying MEPs and basically anyone who will listen to try to raise awareness of the lack of funding for TB …

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