**UPDATE As of 21st Jan 2016 please note the actual structure of BIA 10-2474 changed to this. The continuing follow up to the clinical trial disaster. Chris Southan yesterday suggested I try CID 57880883 as the comparator to CID 54576693 (JNJ-42165279). These have IC50 75 nM vs 350 nM, respectively according to Jannsen’s WO2011139951. Yesterday …