Tag Archive: JNJ-42165279


Differences between similar FAAH inhibitors and their in silico target predictions

**UPDATE As of 21st Jan 2016 please note the actual structure of BIA 10-2474 changed to this. The continuing follow up to the clinical trial disaster. Chris Southan yesterday suggested I try CID 57880883 as the comparator to CID 54576693 (JNJ-42165279).  These have IC50 75 nM vs 350 nM, respectively according to Jannsen’s WO2011139951. Yesterday …

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