I have been a humble participant in several discussions in the last few weeks that have been stimulated by the paper on dispensing and IC50 differences between pipette tips and acoustic handling. I am still parsing them, but what really stands out is the complete lack of exhaustive comparisons in academic screening centers between different …
Tag Archive: HTS
Jul
11
Greater than the sum of the parts – issues in drug discovery
Inspired by the years of reading and also recent collaborative forays into the complexity of data quality and tools used for dispensing in HTS I have started to list issues that we need to be aware of in drug discovery (“anything that can go wrong – which will go wrong”). 1. How you move liquids …