Its been an incredibly fast paced year and hence my posting frequency has suffered. Perhaps its time to get back to writing . Today we had a press release with SRI so that triggered me to fill in the back story. Rewind back to 2014 and the Ebola outbreak was in full flow – see …
Tag Archive: drug discovery
Dec
16
Collaborations Pharmaceuticals, Inc. Announce NIH Award to Develop New Software for Drug Discovery
Today I released the following Collaborations Pharmaceuticals Inc, announcement of our 3rd NIH grant this year. This is an SBIR and will fund software development to provide a tool the company will be able to use in its drug discovery programs but also make commercially available. It will build off our past publications on open …
Mar
26
Whats holding back biopharmaceutical research in the USA?
Wow what a week.. If you were a fly on my wall in my virtual science office you would be blown away. My email has seen it all, my phone conferences have been blistering. But I am about to join the dots – and please give me some leeway, I may have stumbled on to …
Feb
11
A passion for Zika: does anyone want to find an antiviral?
What gets your heart beating fast? For some it is making science progress as fast as they can because life is too short. For me it gets into something totally new and seeing how quickly you can contribute and collaborate with others. How fast can we bring scientists together to do something? I would argue …
Jan
29
Zika Virus – getting some research moving on drug discovery
Following my last post / plea I have been a little preoccupied trying to find scientists that could : 1. contribute to an open Zika virus drug discovery effort 2. Help write a perspective that summarizes potential drug discovery efforts . Fortunately several folks connected by email or twitter to offer ideas and assistance. I …
Jan
26
Creating a rapid response – relevant to Zika virus
I have been following the news on the Zika virus over the last few weeks as it has spread with travelers returning from trips and women giving birth to children with microcephaly. Along with it is a spreading underlying fear of where it will lead. Its not so long ago that Ebola, was grabbing headlines. …
Oct
05
Nobel prize in medicine – going back to natural products for drugs
Every year there are potentially 1000’s of scientists that could have won the Nobel prize and did not. This year the prize recognizes 3 scientists for their work on parasitic diseases. William Campbell and Satoshi Omura won for their work on discovering Avermectin which lead to treatments for River Blindness and Lymphatic Filariasis. Youyou Tu …
May
07
The Necessary – a provocative vision of the scientific future
I was asked by Barry Bunin a few months ago to provide a short presentation on a vision for the future of drug discovery which I finally gave this week. After thinking about this for a while and chatting with a few friends including Alex Clark, – I wondered what was necessary in the future …
Dec
09
Why Are We Still Doing Industrial Age Drug Discovery For Neglected Diseases in The Information Age?
Modern Times, one of my favorite Charlie Chaplin films was the latest inspiration for a little set of slides that summarizes a developing set of ideas for neglected disease research, specifically the focus is open TB research. Some of our recent work on TB machine learning for lead optimization here and Fusing datasets here builds …
Jul
11
Greater than the sum of the parts – issues in drug discovery
Inspired by the years of reading and also recent collaborative forays into the complexity of data quality and tools used for dispensing in HTS I have started to list issues that we need to be aware of in drug discovery (“anything that can go wrong – which will go wrong”). 1. How you move liquids …
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