Category Archive: repurposing

Jan
09

Paper on NCATS structures – collaboration in action

Finally, after a little while our paper on the NCATS and MRC industry provided reagents is now in the latest issue of DDT. I will let it speak for itself and we will present on it at the ACS. This pretty much brings us full circle from my first blog on this topic. Needless to say, …

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Jan
03

Talks at upcoming ACS in April

To quickly follow the last blog of 2012…I was a little backlogged in December and wanted to highlight the talks coming at the ACS in April but just did not get chance to. Another bumper meeting with 6 talks highlighting lots of collaborative projects on Tuberculosis (models, TB mobile), Data quality, repurposing, etc..look forward to …

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Dec
31

End of year blog

Just hours to go till 2013 begins and I am continuing my holiday travel in the passenger seat..rewinding through the fun blogs from the last 12 months and thinking how I never imagined writing about some of the topics. Perhaps some I should have left well alone but there is no going back now! Here …

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Nov
09

I have seen the future – Solutions are more newsworthy than problems

A small thought has been burning away inside..I like many am profoundly interested in the future and in finding solutions to problems. This predominantly happens through collaboration. Collaboration which is a 2 way process. At the moment based on what makes news, developing solutions and solving problems is hardly news worthy. I have mentioned before how we and …

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Nov
05

Why is it difficult to publish on disruptive strategies?

Nearly a year ago a few collaborators had written some ideas down on what we thought could be disruptive strategies to remove bottlenecks in drug discovery. We submitted the paper to Science. As I blogged back in March, the paper was reviewed and rejected. I even posted the email trail. We respectfully did not agree with the …

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Oct
04

NCATs repurposing efforts – the story continues

It seems not a week goes by without some mention of the NCATS library of industry provided reagents in the media. I have blogged about this previously and initially I called for us to petition them due to the lack of structures. Honestly I think there should have been someone at NCATS that took a stand and said this is …

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Sep
30

Wet and dry: or how I left the bench and started to love the blobs

I have never really thought to analyze why I shifted from doing ‘wet’ science at the bench to  ‘dry’ science in front of a computer. A trip to get a flu shot this weekend brought it all back. A relatively simple question “do you have a latex allergy”? Well yes my hands crack after wearing latex …

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Sep
11

Amazing challenges for rare disease groups and how collaborations could help

You know that moment of the day …when you rewind back to 6.30 am – the painful wakeup; the 7 am teleconf (that does not start till 7.30 because of connection problems between NJ, Europe and everyone else) that lasted for 6 hrs; then the hop in the car and drive to a conference at …

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Aug
21

Collaborations to get the NCATS Library of Industry provided reagents

Its seems a while since I blogged on the absolutely bizarre posting of 58 molecules as the ‘library of industry provided reagents’ to be used as a starting point for repurposing – without posting structures. Since my last Blog I have become aware of at least 3 specific groups trying to collate the molecules, Tudor …

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