What gets your heart beating fast? For some it is making science progress as fast as they can because life is too short. For me it gets into something totally new and seeing how quickly you can contribute and collaborate with others. How fast can we bring scientists together to do something? I would argue …
Category Archive: open drug discovery teams
Sep
11
C&EN’s Advances in Drug Discovery and Development
Next Thursday at 10am EST I will be giving a virtual seminar at this virtual symposium – you can find out more and see all the other speakers too. This is a first for me – So I hope for some interaction via Twitter #CENSYM15 Slides are done, now I just have to prepare what …
Nov
04
App exposure
It is the little things in life that make it all worthwhile – perhaps. I have noticed a definite uptick in interest in the science apps we developed over the last few years. For example I was recently contacted by a science writer who wanted to write about the open drug discovery teams app. This …
Aug
25
PLOS paper going viral?
There is just too much going on now with the whole Ebola virus outbreak and the ALS Ice bucket challenge to really use the word “viral”, but I will use it regardless. Last Thursday at 2pm a small editorial co-authored with Ethan Perlstein went live at PLOS Computational Biology about ten simple rules for live …
Aug
21
Anatomy of a PLOS Computational Biology Paper
I think the following is a fair representation of what kicked off the very short editorial paper published today in PLOS Computational Biology. In addition the timeline gives an idea that coming up with the manuscript was quick relative to publication but isn’t that always how it is, the idea is easy relative to getting …
Mar
05
Adding new diseases to the ODDT App
Perhaps not surprisingly with all the activity around Rare Disease day over the last month, I have focused on this and it does not appear to be slowing down in terms of momentum. I was contacted today by a representative of a rare disease foundation to request adding their disease into the ODDT app. Over …
Feb
12
World Symposium 2014
This week I am in Sunny San Diego for the World Symposium 2014, which is focused on the Lysosomal Disease Network. The days are full of 15 minute talks and no parallel sessions. There is a good mixture of younger and established scientists presenting, although the quality is OK, there are some useful talks to …
Feb
03
A rare disease a day: Hunter Syndrome
February is a pretty big month for several reasons. First there is the World Symposium 2014 in San Diego (Feb 10-13) which focuses on Lysosomal Storage Diseases (LSDs). Then at the end of the month is the NIH rare disease day (Feb 28). I will be attending these events and presenting posters. So in honor …
Jan
28
Readying for a busy Rare Disease month
February I will be at World Symposium 2014 to represent the various rare disease groups I have been working with, but more generally I will be interested in the progress this community has made since the meeting last year. I will be presenting one poster on the ODDT app and how it has grown to …
Jan
23
The Non-Drowsy Chaperone
Digging through the recent literature for lysosomal diseases, something caught my attention. I have a bit of an interest in following the progress in finding chaperones for diseases like Sanfilippo syndrome and others. Chaperones are primarily small molecules that may help a protein fold and stabilize it. I first became aware of this when I …
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