Category Archive: ebola

Nov
10

Antimalarial being tested as possible Ebola virus drug -project started with a tweet

Today we announced a new R21 grant from NCATS NIH awarded to Collaborations Pharmaceuticals, Inc andTexas Biomedical Research Institute. This continues the work published in F1000Research . What is missing from the press release and papers etc. is the back story. Why are we working on this and how did it start. Essentially it took …

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Jan
06

Select antimalarials saved lives of those infected with Ebola Virus

Lets start 2016 with a bang. Frequent Ebola collaborator Dr. Megan Coffee just pointed me to a new article in the New England Journal of Medicine that showed a ‘natural experiment’ of how fewer Ebola patients died if treated with artesunate-amodiaquine compared with artemether-lumefantrine. This is fascinating because it goes some way to verify work …

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Dec
28

2015 in review

2015 saw the continuation of some research¬†themes from 2014, namely some work on Ebola, rare diseases and Bayesian models for neglected diseases. At the end of the year several papers are in press for next year so more to come. As usual there were some ups and downs in getting some of these to see …

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Oct
20

Collaboration to find compounds active against Ebola

Our latest contribution to the Ebola literature came out today. A collaboration with Peter Madrid (SRI International), Robert Davey and Manu Anantpadma (Texas Biomedical Research Institute), Alex Clark (Molecular Materials Informatics) and Joel Freundlich (Rutgers). Last year I posted a few times on Ebola here, here¬† here and here. This interest all stemmed from some …

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Sep
11

C&EN’s Advances in Drug Discovery and Development

Next Thursday at 10am EST I will be giving a virtual seminar at this virtual symposium – you can find out more and see all the other speakers too. This is a first for me – So I hope for some interaction via Twitter #CENSYM15 Slides are done, now I just have to prepare what …

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Aug
20

ACS 2015, chemistry talks, posters and Tattoo!

I am just back from a very busy trip to Boston for the ACS. It was great to meet up with many people I see only rarely, at these meetings as well as meet new people including one with a molecule tattoo that got a lot of interest on Twitter . I gave 5 talks …

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Aug
11

My updated schedule for the ACS Boston meeting

Well next week it is the ACS in Boston and of course I leave it to the week before to pull everything together. I initially put up here my listing of abstracts titles etc back in May. This has now been updated a bit to include additional talk and poster showings as well as times …

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May
26

A triple life in science

Ever since embarking on my pretty unusual career path in leaving big pharma in 2001, I have been faced with several forks in the road, hard decisions on which way to go. To join a software company or not? work with university spin out? – some were good decisions others less so. Since 2008 I …

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May
18

Contrasts in Pharmacology 2.0

Last week I was in Turin to give a talk at the Contrasts in Pharmacology 2.0 meeting, organized by the Fondazione Internazionale Menarini. My talk title was provided to me “Bigger data to increase drug discovery”. I am grateful to the organizers for inviting me and was honored to be there alongside speakers from the …

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May
12

Papers and posters for ACS Boston 2015

It is that time of the year when we get those automated emails telling us our abstracts have been scheduled for the next ACS in August. In addition to these I will be participating in a careers panel for undergraduates which will be interesting – hopefully to inspire the next generation that there is lots …

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