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Latest posts

  1. A Rare Breed — April 27, 2018
  2. Voucher roller coaster ride — April 18, 2018
  3. Getting to an in vivo active compound — December 7, 2017
  4. Seeing through the hype of deep learning for drug discovery — June 26, 2017
  5. A Dying Breed — May 25, 2017

Most commented posts

  1. Beware Rare Disease Foundations – Funding Scam — 16 comments
  2. Collaboration could give us a gold standard database of drugs — 15 comments
  3. Green Chemistry – Solvent selection guide — 11 comments
  4. Lets do it all again updating predictions for the ‘real’ BIA 10-2474 — 10 comments
  5. Survey Overload for Scientists – A Language Discrimination Survey — 9 comments

Author's posts listings

Apr
27

A Rare Breed

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I have been doing a lot of reading lately after a period last year when I did not touch a book. Mostly these books are related to science and published in the last year and I am devouring them at a rate of one per week or two. A recent one was very compelling and …

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Apr
18

Voucher roller coaster ride

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Its been a while since my last post here but its getting harder to find time between the 2 companies and writing grants. But one of the most interesting things I have been watching has been the roller coaster ride of the Pediatric Rare Disease priority review vouchers over a few years. The most recent …

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Dec
07

Getting to an in vivo active compound

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Its been an incredibly fast paced year and hence my posting frequency has suffered. Perhaps its time to get back to writing . Today we had a press release with SRI so that triggered me to fill in the back story. Rewind back to 2014 and the Ebola outbreak was in full flow – see …

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Jun
26

Seeing through the hype of deep learning for drug discovery

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The frequency seems to be increasing where I see something that sets me off (head in hands saying why, why why?)..Over the past few years I have seen AI/ Deep Learning and drug discovery appearing often and that may not be a good thing. Now this could be the PR engines of the VC’s, companies …

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May
25

A Dying Breed

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If you have ever wondered how the pill you are taking for your disease originated, then nowadays you don’t have to go far to find out, as a quick search of Wikipedia will return the molecule, who makes it, and a wide array of prescribing information and warnings. This has not always been the case, …

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Apr
20

Summer intern for Collaborations Pharmaceuticals

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We are seeking a Biochemist or Chemist (Masters/PhD) for a summer intern assignment in our Raleigh NC offices.  The duties of the scientist will be to assist with expert data curation for computational modelling of rare and neglected diseases. This position is ideal for a Masters or PhD student in the RTP or Triad area …

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Mar
16

Drug Discovery Today Special Issue on Tuberculosis

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Today a special issue of Drug Today Today was published. I was  the editor of this issue and honored that so many colleagues from our European funded MM4TB and other European projects agreed to provide articles on their contributions to Tuberculosis drug discovery. Through collaborations I was directly involved in providing 3 articles and an …

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Mar
09

A bit of an update on Collaborations Pharmaceuticals

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Its been a few months since the last post. In that time Collaborations Pharmaceuticals has been working flat out. We hired a Postdoc and associate and have been keeping our heads down working on the 3 NIH grants with collaborators. Next week I will be representing the team at the Gordon Conference on Tropical infectious diseases and …

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Jan
18

Post doctoral position on chaperone development for neurological disorders

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I would like to highlight an open postdoc position in the lab of a close collaborator Dr. Alexey Pshezhetsky Open position: Postdoctoral fellow or Ph.D. student Supervising researcher and laboratory: Dr. Alexey Pshezhetsky, laboratory studying lysosomal biology and metabolic disorders, Research Center of CHU Sainte-Justine Project length: 1 year with renewal opportunity Start date: Immediately …

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Dec
20

Small Molecule Bioactivity Databases Book Chapter

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Its been a busy year transitioning from spending most of my time with CDD to my start-up Collaborations Pharmaceuticals, Inc etc. Along the way I found time to write a few book chapters. One of these recently published in High Throughput Screening Methods : Evolution and Refinement Editors: Joshua A Bittker, Nathan T Ross Our …

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